PUBLICATIONS
New publications coming soon!
2021-2023
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S. W. Hulbert, P. Desai, M. C. Jewett, M. P. DeLisa, A. J. Williams “Glycovaccinology: The design and engineering of carbohydrate-based vaccine components” Biotechnology Advances (2023). [Link]
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A. J. Williams, K. F. Warfel, P. Desai, J. Li, J. Lee, D. A. Wong, S. E. Sobol, M. C. Jewett, Y. Chang, M. P. DeLisa “A low-cost recombinant glycoconjugate vaccine confers immunogenicity and protection against enterotoxigenic Escherichia coli infections in mice” Frontiers in Molecular Biosciences (2023). [Link]
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K. F. Warfel, A. Williams, D. A. Wong, S. E. Sobol, A. S. Karim, M. P. DeLisa, M. C. Jewett “A low-cost, thermostable, cell-free protein synthesis platform for on-demand production of glycoconjugate vaccines” ACS Synthetic Biology (2023). [Link]
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X. Fu, A. Williams, J. Pieracci, M. Bakhshayeshi “Leveraging High-Throughput Purification to Accelerate Viral Vector Process Development” Journal of Chromatography A (2022). [Link]
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A. Badri, A. Williams , W. He, K. Fraser, J. S. Dordick, R. J. Linhardt, M. A. G. Koffas “Complete biosynthesis of a sulfated glycosaminoglycan in Escherichia coli” (2021). [Link]
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Abinaya Badri, Mattheos AG KOFFAS, Robert John Linhardt, Asher J Williams
US Patent Office Application # 17641675 - [Link]
2015-2020
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. Olmsted, C. Stigliano, A. Badri, F. Zhang, A. Williams, M. A. G. Koffas, Y. Xie, R. J. Linhardt, J. Cibelli, P. Horner “Fabrication of homotypic neural ribbons as a multiplex platform optimized for spinal cord delivery” Nature Scientific Reports (2020). [Link]
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D. G. Shastry, F. J. Irudayanathan, A. Williams, M. A. G. Koffas, R. J. Linhardt, S. Nangia, P. Karande “Rational identification and characterization of peptide ligands for targeting polysialic acid”, Nature Scientific Reports (2020). [Link]
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A. Williams, K. S. Gedeon, D. Vaidyanathan, Y. Yu, C. Collins, J. S. Dordick, R. J. Linhardt, M. A.G. Koffas “Metabolic Engineering of Bacillus megaterium for Heparosan Biosynthesis using Pasteurella multocida Heparosan Synthase, PmHS2”, Microbial Cell Factories (2019). [Link]
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A. Badri, A. Williams, K. Xia, R. J. Linhardt, M. A. G. Koffas “Increased 3’phosphoadenosine-5’-phosphosulfate levels in engineered Escherichia coli facilitates in vitro synthesis of Chondroitin Sulfate A”, Biotechnology Journal (2019). [Link]
**Cover image design for this issue on Systems Metabolic Engineering [Link]
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Y. Yu, A. Williams, X. Zhang L. Fu, K. Xia, Y. Xu, F. Zhang, J.Liu, M. A. G. Koffas, R. J. Linhardt “Specificity and action pattern of heparanase Bp, a β-glucuronidase from Burkholderia pseudomallei”, Glycobiology (2019). [Link]
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S. Kim, J. Kundu, A. Williams, A. S. Yandulskaya, J. R. Monaghan, R. L. Carrier, R. J. Linhardt “Glycosaminoglycans compositional analysis of urodele axolotl (Ambystoma mexicanum) and porcine retina”, Glycoconjugate Journal (2019). [Link]
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B. F. Cress, U. Bhaskar, D. Vaidyanathan, A. Williams, C. Cai, X. Liu, L. Fu, V. M-Chari, F. Zhang, S. A. Mousa, J. S. Dordick, M. A. G. Koffas, R. J. Linhardt “Heavy heparin, a stable isotpope-enriched, chemoenzymatically-synthesized poly-component drug”, Angewandte Chemie (2019). [Link]
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A. Williams, R. J. Linhardt, M. A.G. Koffas “Metabolic Engineering of Capsular Polysaccharides”, Emerging Topics in Life Sciences (2018). [Link]
**Cover image design for this issue on Systems Metabolic Engineering [Link]
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A. Badri, A. Williams, R. J. Linhardt, M. A.G. Koffas “The Road to Animal-Free Glycosaminoglycan Production: Current Efforts and Bottlenecks”, Current Opinion in Biotechnology (2018). [Link]
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A. Williams, W. He, B. F. Cress, X. Liu, J. Alexandria, H. Yoshizawa, K. Nishimura, T. Toida, M. A. G. Koffas, R. J. Linhardt “Cloning and expression of recombinant chondroitinase AC II and its comparison to the Arthrobacter aurescens enzyme”, Biotechnology Journal (2017). [Link]
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D. Vaidyanathan, A. Williams, J. S. Dordick, M. A.G. Koffas, R. J. Linhardt “Engineered heparins as new anticoagulant drugs", Bioengineering & Translational Medicine (2016). [Link]
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B. Pierre, J. W. Labonte, T. Xiong, E. Aoraha, A. Williams, V. Shah, E. Chau, K. Y. Helal, J. Gray, J. R. Kim "Molecular determinants for protein stabilization by insertional-fusion to a thermophilic host protein", ChemBioChem (2015). [Link]